Short answer: Azithromycin and clarithromycin are close cousins, but they are not interchangeable. Azithromycin needs fewer days of treatment, is gentler on other medications, and is usually the more convenient

Few antibiotics have a nickname as famous as the “Z-Pak.” The small blister card of six tablets has become shorthand for “a quick course of antibiotics” in American medicine cabinets.

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